The functional impact of migraine during and between attacks can be measured using the Migraine-Specific Quality-of-Life Questionnaire (MSQ)1-3
The MSQ RF-R is a valid measure of the functional impact of migraine1,2
This tool consists of 7 questions that assess how migraine limits the social and work-related activities of patients. Patient responses are rated on a 100-point scale, with 0 points being most impacted and 100 points being least impacted.1,2
The questions of the RF-R domain of the MSQ v2.1 include1:
- Have migraines interfered with how well you dealt with family, friends, and others who are close to you?
- Have migraines interfered with your leisure time activities, such as reading or exercising?
- Have you had difficulty in performing work or daily activities because of migraine symptoms?
- Did migraines keep you from getting as much done at work or at home?
- Did migraines limit your ability to concentrate on work or daily activities?
- Have migraines left you too tired to do work or daily activities?
- Have migraines limited the number of days you felt energetic?
For patients with 4-14 MHDs per month,
Emgality significantly improved patients' migraine-specific quality of life during and in between attacks2,3
Baseline: 51.4 points vs 52.9 points
Baseline: 52.5 points vs 51.4 points
- In REGAIN, statistical significance vs placebo was not observed after controlling for multiple comparisons for mean change in MSQ v2.1 RF-R3
See study designs for EVOLVE-1 and EVOLVE-2 and REGAIN.